- 名称:FRAX597
- 简介:FRAX597, a small-molecule pyridopyrimidinone, is a potent and ATP competitive inhibitor of the group I PAKs (PAK1 IC50= 8 nM, PAK2 IC50= 13 nM, PAK3 IC50= 19 nM).
- CASNO:1286739-19-2
- 分子式:C29H28ClN7OS
- 分子量:558.1
- SMILES:CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)C4=CN=CS4)Cl)NC5=CC=C(C=C5)N6CCN(CC6)C
- 保持条件:at -20°C 3 years Powder
- 同名:FRAX 597, FRAX-597
- 纯度:>98%
- 应用:PAK inhibitor
- 作用机制:Inhibitor