• 名称：GSK481
• 简介：GSK481 is a novel benzoxazepinone (BOAz) series of RIP1 inhibitors. Receptor Interacting Protein Kinase 1 (RIP1) has been implicated as a key contributor to inflammation through the regulation of programmed necrosis. Inhibition of this kinase has been shown to hinder cell necrotic death, thereby establishing RIP1 as a viable target for the potential treatment of multiple inflammatory diseases.
• CASNO：1622849-58-4
• 分子式：C21H19N3O4
• 分子量：377.39
• SMILES：O=C(C1=NOC(CC2=CC=CC=C2)=C1)N[C@H]3COC4=CC=CC=C4N(C)C3=O
• 保持条件：at -20°C 3 years Powder
• 同名：GSK 481, GSK-481
• 纯度：>98%
• 应用：RIP1 inhibitor
• 作用机制：Inhibitor