- 名称:SCH 442416
- 简介:SCH 442416 is a selective adenosine A2A receptor antagonist; binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). Displays > 23000-fold selectivity for hA2A over hA1 in vitro with minimal affinity for hA2B and hA3 receptors (IC50 > 10 μM).
- CASNO:316173-57-6
- 分子式:C20H19N7O2
- 分子量:389.42
- SMILES:COC1=CC=C(C=C1)CCCN2C3=C(C=N2)C4=NC(=NN4C(=N3)N)C5=CC=CO5
- 保持条件:at -20°C 3 years Powder
- 同名:SCH442416, SCH-442416
- 纯度:>98%
- 应用:A2A Receptor Antagonist
- 作用机制:Antagonist