• 名称：GSK-J4
• 简介：GSK J4 is a cell permeable prodrug rapidly hydrolyzed by macrophage esterases to GSK-J1, a potent selective jumonji H3K27 demethylase inhibitor; attenuates lipopolysaccharide (LPS)-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 uM for the inhibition of TNF?? release).
• CASNO：1373423-53-0
• 分子式：C24H27N5O2
• 分子量：417.5
• SMILES：CCOC(=O)CCNC1=NC(=NC(=C1)N2CCC3=CC=CC=C3CC2)C4=CC=CC=N4
• 保持条件：at -20°C 3 years Powder
• 同名：GSK J4
• 纯度：>98%
• 应用：Demethylase Inhibitor
• 作用机制：Inhibitor