- 名称:IWR-1-endo
- 简介:IWR-1-endo is a potent inhibitor of the Wnt response, blocking a cell-based Wnt/β-catenin pathway reporter response with an IC50 value of 180 nM. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to β-catenin activation of gene transcription.
- CASNO:1127442-82-3
- 分子式:C25H19N3O3
- 分子量:409.44
- SMILES:C1C2C=CC1C3C2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6
- 保持条件:at -20°C 3 years Powder
- 同名:N/A
- 纯度:>98%
- 应用:Wnt inhibitor
- 作用机制:Inhibitor