• 名称：Letaxaban (TAK-442)
• 简介：Letaxaban, also known as TAK-442, is a potent, selective, and orally active factor Xa inhibitor, which is a tetrahydropyrimidin-2(1H)-one derivative. TAK-442 inhibited endogenous FXa activity in platelet-poor human [half-maximal inhibitory concentration (IC(50)): 53 nM, TAK-442] and rat (IC(50): 32 nM, TAK-442) plasma.
• CASNO：870262-90-1
• 分子式：C22H26ClN3O5S
• 分子量：479.98
• SMILES：C1CNC(=O)N(C1)C2CCN(CC2)C(=O)[C@@H](CS(=O)(=O)C3=CC4=C(C=C3)C=C(C=C4)Cl)O
• 保持条件：at -20°C 3 years Powder
• 同名：TAK 442; TAK442
• 纯度：>98%
• 应用：factor Xa inhibitor
• 作用机制：Inhibitor