- 名称:Batimastat (BB-94)
- 简介:Batimastat (BB-94) is a potent and synthetic inhibitor of a broad spectrum of matrix metalloproteinases (MMPs), including interstitial collagenase (IC50 = 3 nM), stromelysin (IC50 = 20 nM), Mr 72,000 type IV collagenase (IC50 = 4 nM), Mr 92,000 type IV collagenase (IC50 = 4 nM), and matrilysin (IC50 = 6 nM). It is a low-molecular-weight (MW = 478) and peptide-like collagen substrate analogue consisting of a peptide backbone and a hydroxamic acid group which bind to MMPs and the catalytically active zinc atom respectively.
- CASNO:130370-60-4
- 分子式:C23H31N3O4S2
- 分子量:477.64
- SMILES:CC(C)C[C@H]([C@H](CSC1=CC=CS1)C(=O)NO)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)NC
- 保持条件:at -20°C 3 years Powder
- 同名:BB 94
- 纯度:>98%
- 应用:MMP inhibitor
- 作用机制:Inhibitor