• 名称：Raxatrigine (GSK1014802)
• 简介：Raxatrigine (GSK1014802) is a novel sodium channel blocker and is an effective anticonvulsant agent. In rats, GSK1014802 (20 - 80 mg/kg p.o.) attenuated the deficit in reversal learning induced by phencyclidine (PCP) in a dose-dependent way, which suggested the potential of GSK1014802 in the treatment of cognitive symptoms of schizophrenia. GSK2 was also a potent inhibitor of human MAO-B with pIC50 value of 7.96 but did not inhibit human MAO-A.
• CASNO：934240-30-9
• 分子式：C18H19FN2O2
• 分子量：314.35
• SMILES：FC1=CC=CC=C1COC2=CC=C([C@@](N3)([H])CC[C@@]3([H])C(O)=N)C=C2
• 保持条件：at -20°C 3 years Powder
• 同名：GSK1014802, GSK-1014802, GSK 1014802
• 纯度：>98%
• 应用：Sodium channel blocker
• 作用机制：Blocker