• 名称：CO-1686 (Rociletinib, AVL-301)
• 简介：CO-1686 is a novel, oral, targeted covalent (irreversible) inhibitor of the cancer-causing mutant forms of epidermal growth factor receptor (EGFR) currently being studied for the treatment of non-small cell lung cancer (NSCLC).
• CASNO：1374640-70-6
• 分子式：C27H28F3N7O3
• 分子量：555.55
• SMILES：CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F)OC
• 保持条件：at -20°C 3 years Powder
• 同名：CO1686; AVL-301; CNX-419 ;AVL 301; AVL301; CNX419
• 纯度：>98%
• 应用：EGFR inhibitor
• 作用机制：Inhibitor