- 名称:SANT-1
- 简介:SANT-1 is a potent, cell-permeable inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (KD = 1.2 nM). Inhibits smoothened agonist effects with an IC50 of 20 nM (in Shh-LIGHT2 cells).
- CASNO:304909-07-7
- 分子式:C23H27N5
- 分子量:373.5
- SMILES:CC1=C(C(=NN1C2=CC=CC=C2)C)/C=N/N3CCN(CC3)CC4=CC=CC=C4
- 保持条件:at -20°C 3 years Powder
- 同名:SANT 1, SANT1
- 纯度:>98%
- 应用:Sonic hedgehog inhibitor
- 作用机制:Inhibitor