- 名称:PHA 408
- 简介:PHA 408 is a potent, highly selective and ATP-competitive IKB kinase-2 (IKK-2) inhibitor (IC50: 40 nM), which binds IKK-2 tightly with a relatively slow off rate; highly recommended tool to investigate the mechanisms by which IKK-2 regulates NF-KB signaling.
- CASNO:503555-55-3
- 分子式:C29H27ClFN7O2
- 分子量:560.02
- SMILES:CN1CCN(CC1)C2=NC=C(C(=C2)C(=O)NC3=CC4=C(CCC5=C4N(N=C5C(=O)N)C6=CC=C(C=C6)F)C=C3)Cl
- 保持条件:at -20°C 3 years Powder
- 同名:PHA-408, PHA408
- 纯度:>98%
- 应用:IKK-2 inhibitor
- 作用机制:Inhibitor