• 名称：MK-6096 (Filorexant)
• 简介：MK6096, also known as filorexant, is an orally bioavailable potent and selective reversible antagonist of OX(1)R and OX(2)R currently in clinical development for insomnia. MK-6096 demonstrated potent binding and antagonism of both human OX(1)R and OX(2)R (<3 nM in binding, 11 nM in FLIPR), with no significant off-target activities against a panel of >170 receptors and enzymes.
• CASNO：1088991-73-4
• 分子式：C24H25FN4O2
• 分子量：420.48
• SMILES：CC1=CC=C(C2=NC=CC=N2)C(C(N3C[C@@H](COC4=NC=C(F)C=C4)CC[C@@H]3C)=O)=C1
• 保持条件：at -20°C 3 years Powder
• 同名：MK6096, MK-6096, MK 6096
• 纯度：>98%
• 应用：Orexin receptor antagonist
• 作用机制：Antagonist