• 名称：RI-1
• 简介：RI-1 is a small molecule that inhibits the central recombination protein RAD51. RI-1 specifically reduces gene conversion in human cells while stimulating single strand annealing. RI-1 binds covalently to the surface of RAD51 protein at cysteine 319 that likely destabilizes an interface used by RAD51 monomers to oligomerize into filaments on DNA.
• CASNO：415713-60-9
• 分子式：C14H11Cl3N2O3
• 分子量：361.61
• SMILES：C1COCCN1C2=C(C(=O)N(C2=O)C3=CC(=C(C=C3)Cl)Cl)Cl
• 保持条件：at -20°C 3 years Powder
• 同名：RI1?? RI 1
• 纯度：>98%
• 应用：RAD51 Inhibitor II
• 作用机制：Inhibitor