• 名称：KU 0060648
• 简介：KU0060648 is a potent and selective inhibitor of DNA-dependent protein kinase (DNA-PK), (IC50 = 8.6 nM); with 20-1000 fold selectivity for DNA-PK over other PIKKs and a panel of 60 kinases. KU-0060648 enhances HDR efficiency and attenuates NHEJ frequency.
• CASNO：881375-00-4
• 分子式：C33H34N4O4S.3HCl
• 分子量：692.1
• SMILES：CCN1CCN(CC1)CC(=O)NC2=C3C4=CC=CC=C4SC3=C(C=C2)C5=CC=CC6=C5OC(=CC6=O)N7CCOCC7
• 保持条件：at -20°C 3 years Powder
• 同名：KU0060648, KU-0060648
• 纯度：>98%
• 应用：DNA-PK inhibitor
• 作用机制：Inhibitor