• 名称：TAK-632
• 简介：TAK-632 is a potent pan-RAF inhibitor with favorable in vitro activity (BRAF(V600E) IC50, 2.4 nM; BRAF(wt), 8.3 nM; CRAF, 1.4 nM; pMEK (A375) IC50, 12 nM; pMEK (HMVII), 49 nM; V/B ratio.
• CASNO：1228591-30-7
• 分子式：C27H18F4N4O3S
• 分子量：554.51
• SMILES：C1CC1C(=O)NC2=NC3=C(S2)C(=C(C=C3)OC4=CC(=C(C=C4)F)NC(=O)CC5=CC(=CC=C5)C(F)(F)F)C#N
• 保持条件：at -20°C 3 years Powder
• 同名：TAK 632; TAK632
• 纯度：>98%
• 应用：pan-RAF inhibitor
• 作用机制：Inhibitor