- 名称:NU 9056
- 简介:NU9056 is an selective KAT5 (Tip60) HAT inhibitor. IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively. Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.
- CASNO:Not Available
- 分子式:C6H4N2S4
- 分子量:232.37
- SMILES:C1(SSC2=CC=NS2)=CC=NS1
- 保持条件:at -20°C 3 years Powder
- 同名:NU9056, NU-9056
- 纯度:>98%
- 应用:KAT5 (Tip60) HAT inhibitor
- 作用机制:Inhibitor