- 商品货号:A13403
- 名称:ZCL-278
- 简介:ZCL-278 is a selective inhibitor of Cdc42. Targets the binding site of the Cdc42 guanine nucleotide exchange factor, intersectin (ITSN). Inhibits Cdc42-mediated cellular effects, including microspike formation in 3T3 fibroblasts and neuronal branching in primary neonatal cortical neurons. Also suppresses cell motility and migration in PC3 cells, without cytotoxic effects.
- CASNO:587841-73-4
- 分子式:C21H19BrClN5O4S2
- 分子量:584.89
- SMILES:CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)NC(=S)NC(=O)COC3=C(C=C(C=C3)Br)Cl)C
- 保持条件:at -20°C 3 years Powder
- 同名:ZCL278, ZCL 278
- 纯度:>98%
- 应用:Cdc42 GTPase inhibitor
- 作用机制:Inhibitor