• 名称：Brigatinib (AP26113)
• 简介：Brigatinib (AP26113) is a potent and selective ALK (IC50, 0.6 nM) and ROS1 (IC50, 0.9 nM) inhibitor. It also inhibits ROS1, FLT3, and mutant variants of FLT3 (D835Y) and EGFR with lower potentcy.
• CASNO：1197953-54-0
• 分子式：C29H39ClN7O2P
• 分子量：584.09
• SMILES：CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)NC5=CC=CC=C5P(=O)(C)C)Cl)OC
• 保持条件：at -20°C 3 years Powder
• 同名：AP-26113, AP 26113, AP26113
• 纯度：>98%
• 应用：ALK Inhibitor
• 作用机制：Inhibitor