- 名称:GS-9256
- 简介:GS-9451 is a potent macrocyclic HCV NS3 PI that achieved a median maximal change in HCV RNA of 3.6 log10 IU/mL (range, -4.7 log10 to -3.1 log10 IU/mL) following 3-day monotherapy in treatment-nave patients with HCV genotype 1 infection during phase I.
- CASNO:1001094-46-7
- 分子式:C46H56ClF2N6O8PS
- 分子量:957.461
- SMILES:CC(C)NC1=NC(=CS1)C2=NC3=C(C=CC(=C3Cl)OC)C(=C2)O[C@@H]4C[C@H]5C(=O)N[C@@]6(C[C@H]6CCCCCCC[C@@H](C(=O)N5C4)NC(=O)OC7CCCC7)P(=O)(CC8=C(C=CC=C8F)F)O
- 保持条件:at -20°C 3 years Powder
- 同名:GS 9256, GS9256
- 纯度:>98%
- 应用:HCV NS3 inhibitor
- 作用机制:Inhibitor