- 名称:BI-78D3
- 简介:BI-78D3 is a competitive JNK (c-Jun N-terminal kinases) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. BI 78D3 inhibits JIP1(JNK interacting protein 1)-JNK binding (IC50 = 500 nM).
- CASNO:883065-90-5
- 分子式:C13H9N5O5S2
- 分子量:379
- SMILES:C1COC2=C(O1)C=CC(=C2)N3C(=O)NN=C3SC4=NC=C(S4)[N+](=O)[O-]
- 保持条件:at -20°C 3 years Powder
- 同名:BI 78D3, BI78D3
- 纯度:>98%
- 应用:JNK inhibitor
- 作用机制:Inhibitor