- 名称:AR-A 014418
- 简介:AR-A 014418 is a selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 μM) and over 26 other kinases. Inhibits β-amyloid-mediated neurodegeneration in hippocampal slices.
- CASNO:487021-52-3
- 分子式:C12H12N4O4S
- 分子量:308.31
- SMILES:COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-]
- 保持条件:at -20°C 3 years Powder
- 同名:AR-A014418, ARA 014418, ARA014418
- 纯度:>98%
- 应用:GSK-3 inhibitor
- 作用机制:Inhibitor