• 名称：3-deazaneplanocin A HCl (DZNep HCl)
• 简介：3-deazaneplanocin A, also known as DZNep, is a well-known histone methyltransferase inhibitor, which disrupts polycomb-repressive complex 2 (PRC2), and induces apoptosis, while inhibiting proliferation and metastasis, in cancer cells, including acute myeloid leukemia, breast cancer and glioblastoma.
• CASNO：120964-45-6
• 分子式：C12H15ClN4O3
• 分子量：298.73
• SMILES：C1=CN=C(C2=C1N(C=N2)[C@@H]3C=C([C@H]([C@H]3O)O)CO)N.Cl
• 保持条件：at -20°C 3 years Powder
• 同名：DZNep, NSC 617989
• 纯度：>98%
• 应用：EZH2 inhibitor
• 作用机制：Inhibitor