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Thapsigargin
Thapsigargin
会员等级价V
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  • 商品货号:A14007
  • 名称:Thapsigargin
  • 简介:Thapsigargin is a cell-permeable sesquiterpene lactone found in the roots of Thapsia garganica. It is a tumor promoter and induces the release of intracellular stored Ca2+ without hydrolysis of inositolphospholipids via inhibition of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA, IC50=30 nM).
  • CASNO:67526-95-8
  • 分子式:C34H50O12
  • 分子量:650.75
  • SMILES:CCCCCCCC(=O)O[C@H]1[C@H]2C(=C([C@@H]1OC(=O)/C(=CC)/C)C)[C@H]3[C@]([C@H](C[C@]2(C)OC(=O)C)OC(=O)CCC)([C@](C(=O)O3)(C)O)O
  • 保持条件:at -20°C 3 years Powder
  • 同名:N/A
  • 纯度:>98%
  • 应用:SERCA ATPase inhibitor
  • 作用机制:Inhibitor