- 名称:SL-327
- 简介:SL-327 is a selective inhibitor of MEK1 and MEK2 (IC50 values are 0.18 and 0.22 μM respectively); blocks hippocampal LTP in vitro. Brain penetrant in vivo, blocking fear conditioning and learning in rats, and producing neuroprotection in mice, following systemic administration.
- CASNO:305350-87-2
- 分子式:C16H12F3N3S
- 分子量:335.4
- SMILES:C1=CC=C(C(=C1)C(=C(N)SC2=CC=C(C=C2)N)C#N)C(F)(F)F
- 保持条件:at -20°C 3 years Powder
- 同名:SL 327, SL327
- 纯度:>98%
- 应用:MKK/MEK inhibitor
- 作用机制:Inhibitor