• 名称：SB265610
• 简介：SB 265610 is a nonpeptide, allosteric, inverse agonist of CXCR2 (Kd = 2.51 nM) that prevents receptor activation by binding to a region distinct from the agonist binding site. It does not bind to the related CXCR1 receptor.1 It has been shown to prevent neutrophil chemotaxis both in vitro and in a rat model of hyperoxia-induced lung injury.
• CASNO：211096-49-0
• 分子式：C14H9BrN6O
• 分子量：357.16
• SMILES：C1=CC=C(C(=C1)NC(=O)NC2=CC=C(C3=NNN=C23)C#N)Br
• 保持条件：at -20°C 3 years Powder
• 同名：SB 265610,SB-265610
• 纯度：>98%
• 应用：CXCR2 antagonist
• 作用机制：Antagonist