- 名称:PX-478 HCl
- 简介:PX-478 is HIF-1alpha inhibitor, is also an orally active small molecule with potential antineoplastic activity. PX-478 has excellent activity against established human tumor xenografts, providing tumor regressions with prolonged growth delays which correlate positively with HIF-1 levels. PX-478 is a highly water soluble molecule, with good i.v., i.p. and p.o. antitumor activity.
- CASNO:685898-44-6
- 分子式:C13H20Cl4N2O3
- 分子量:394.12
- SMILES:C1=CC(=CC=C1C[C@@H](C(=O)O)N)[N+](CCCl)(CCCl)[O-].Cl.Cl
- 保持条件:at -20°C 3 years Powder
- 同名:0
- 纯度:>98%
- 应用:HIF-1alpha inhibitor
- 作用机制:Inhibitor