• 名称：SAR156497
• 简介：SAR156497 is an exquisitely selective Aurora A, B, and C inhibitor with in vitro and in vivo efficacy with IC50 = 0.5 nM (Aurora A), 1 nM (Aurora B / incenp), 3 nM (Aurora C / incenp) respectively SAR156497 combines high in vitro potency with satisfactory metabolic stability and limited CYP3A4 and PDE3 inhibition.
• CASNO：1256137-14-0
• 分子式：C27H24N4O4
• 分子量：468.5
• SMILES：O=C(C1=C2NC3=C(C(CCC3)=O)[C@@H](C4=CC=CC(OC5=NC6=CC=CC=C6N5)=C4)C2=CN1)OCC
• 保持条件：at -20°C 3 years Powder
• 同名：SAR-156497, SAR 156497
• 纯度：>98%
• 应用：Aurora Kinase inhibitor
• 作用机制：Inhibitor