- 名称:AVL-292 benzenesulfonate
- 简介:AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM, >1400-fold selectivity over the other kinases assayed.
- CASNO:1360053-81-1
- 分子式:C28H28FN5O6S
- 分子量:581.62
- SMILES:COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F.C1=CC=C(C=C1)S(=O)(=O)O
- 保持条件:at -20°C 3 years Powder
- 同名:AVL292 benzenesulfonate, AVL 292 benzenesulfonate
- 纯度:>98%
- 应用:BTK inhibitor
- 作用机制:Inhibitor