- 名称:LDK378 (Ceritinib) dihydrochloride
- 简介:LDK378 dihydrochloride is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
- CASNO:1380575-43-8
- 分子式:C28H37Cl2N5O3S
- 分子量:594.6
- SMILES:CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl.Cl.Cl
- 保持条件:at -20°C 3 years Powder
- 同名:LDK 378 dihydrochloride, LDK-378 dihydrochloride, Ceritinib dihydrochloride
- 纯度:>98%
- 应用:ALK inhibitor
- 作用机制:Inhibitor