- 名称:MK-8245 Trifluoroacetate
- 简介:MK-8245 trifluoroacetate is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy.
- CASNO:1415559-41-9
- 分子式:C19H17BrF4N6O6
- 分子量:581.27
- SMILES:C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O.C(=O)(C(F)(F)F)O
- 保持条件:at -20°C 3 years Powder
- 同名:MK 8245 Trifluoroacetate, MK8245 Trifluoroacetate
- 纯度:>98%
- 应用:Liver-targeting SCD Inhibitor?
- 作用机制:Inhibitor