• 名称：N-Desethyl Sunitinib
• 简介：N-desethyl sunitinib is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT respectively).
• CASNO：356068-97-8
• 分子式：C20H23FN4O2
• 分子量：370.42
• SMILES：CCNCCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C
• 保持条件：at -20°C 3 years Powder
• 同名：SU11662, SU 11662, SU-11662
• 纯度：>98%
• 应用：VEGFR/PDGFRβ/KIT inhibitor
• 作用机制：Inhibitor