- 名称:NVP-BGJ398 phosphate
- 简介:NVP-BGJ398 phosphate is a novel selective, pan-specific FGFR inhibitor with IC50 of 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively; >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes.
- CASNO:1310746-10-1
- 分子式:C26H34Cl2N7O7P
- 分子量:658.47
- SMILES:CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl.OP(=O)(O)O
- 保持条件:at -20°C 3 years Powder
- 同名:BGJ-398 phosphate, BGJ 398 phosphate, NVP BGJ398 phosphate
- 纯度:>98%
- 应用:FGFR Inhibitor
- 作用机制:Inhibitor