• 名称：NVP-BKM120 Hydrochloride
• 简介：NVP-BKM120 Hydrochloride is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNA-PK, with little activity to PI4Kβ.
• CASNO：1312445-63-8
• 分子式：C18H21F3N6O2.HCl
• 分子量：446.85
• SMILES：C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4.Cl
• 保持条件：at -20°C 3 years Powder
• 同名：BKM-120 hydrochloride, BKM120 hydrochloride, BKM 120 hydrochloride
• 纯度：>98%
• 应用：PI3K Inhibitor?
• 作用机制：Inhibitor