- 名称:AV412
- 简介:AV-412 (MP412) is an EGFR inhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19 nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M?and ErbB2, respectively.
- CASNO:451492-95-8
- 分子式:C27H28ClFN6O
- 分子量:507.02
- SMILES:O=S(C1=CC=C(C)C=C1)(O)=O.C=CC(NC2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2C#CC(N5CCN(C)CC5)(C)C)=O.O=S(C6=CC=C(C)C=C6)(O)=O
- 保持条件:at -20°C 3 years Powder
- 同名:av 412, av-412, MP 412, MP-412
- 纯度:>98%
- 应用:EGFR inhibitor
- 作用机制:Inhibitor