• 名称：AZ5104
• 简介：AZ5104, the demethylated metabolite of AZD-9291, is a potent EGFR inhibitor with IC50 of <1 nM, 6 nM, 1 nM, and 25 nM for EGFR (L858R/T790M), EGFR (L858R), EGFR (L861Q), and EGFR (wildtype), respectively. Phase 1.
• CASNO：1421373-98-9
• 分子式：C27H31N7O2
• 分子量：485.58
• SMILES：CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CNC4=CC=CC=C43)OC
• 保持条件：at -20°C 3 years Powder
• 同名：AZ-5104, AZ 5104
• 纯度：>98%
• 应用：EGFR inhibitor
• 作用机制：Inhibitor