- 名称:EPZ011989
- 简介:EPZ011989 is a potent, selective orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 wt and EZH2 Y646; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.
- CASNO:1598383-40-4
- 分子式:C35H51N5O4
- 分子量:605.81
- SMILES:CCN(C1CCC(CC1)N(C)CCOC)C2=CC(=CC(=C2C)C(=O)NCC3=C(C=C(NC3=O)C)C)C#CCN4CCOCC4
- 保持条件:at -20°C 3 years Powder
- 同名:EPZ-011989, EPZ 011989
- 纯度:>98%
- 应用:EZH2 Inhibitor
- 作用机制:Inhibitor