• 名称：AZD8186
• 简介：AZD8186 is an isoform-specific small-molecule PI3K inhibitor, potently inhibits PI3Kβ (IC50=4 nM) and PI3Kδ (IC50=12 nM) with selectivity over PI3Kα (IC50=35 nM) and PI3Kγ (IC50=675 nM).
• CASNO：1627494-13-6
• 分子式：C24H25F2N3O4
• 分子量：457.47
• SMILES：CC(C1=C2C(=CC(=C1)C(=O)N(C)C)C(=O)C=C(O2)N3CCOCC3)NC4=CC(=CC(=C4)F)F
• 保持条件：at -20°C 3 years Powder
• 同名：AZD 8186, AZD-8186
• 纯度：>98%
• 应用：PI3K inhibitor
• 作用机制：Inhibitor