• 名称：BI-847325
• 简介：BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Phase 1.
• CASNO：1207293-36-4
• 分子式：C29H28N4O2
• 分子量：464.56
• SMILES：CCNC(C#CC1=CC=C2C(NC(/C2=C(NC3=CC=C(CN(C)C)C=C3)/C4=CC=CC=C4)=O)=C1)=O
• 保持条件：at -20°C 3 years Powder
• 同名：BI 847325, BI847325
• 纯度：>98%
• 应用：MEK/Aurora Inhibitor
• 作用机制：Inhibitor