• 名称：Entrectinib
• 简介：Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well as ROS1 and ALK, with high potency and selectivity.
• CASNO：1108743-60-7
• 分子式：C31H34F2N6O2
• 分子量：560.64
• SMILES：CN1CCN(CC1)C2=CC(=C(C=C2)C(=O)NC3=NNC4=C3C=C(C=C4)CC5=CC(=CC(=C5)F)F)NC6CCOCC6
• 保持条件：at -20°C 3 years Powder
• 同名：RXDX-101, RXDX-101, RXDX-101, NMS E628, NMS-E628, NMSE628
• 纯度：>98%
• 应用：TRK, ROS1, ALK inhibitor
• 作用机制：Inhibitor