- 名称:EPI-001
- 简介:EPI-001 is an antagonist of the androgen receptor (AR) that acts by binding covalently to the N-terminal domain (NTD) of the AR and blocking protein-protein interactions required for transcriptional activity of the AR and its splice variants (IC50 for inhibition of AR NTD transactivation ?? 6 μM)
- CASNO:227947-06-0
- 分子式:C21H27ClO5
- 分子量:394.89
- SMILES:CC(C)(C1=CC=C(C=C1)OCC(CO)O)C2=CC=C(C=C2)OCC(CCl)O
- 保持条件:at -20°C 3 years Powder
- 同名:EPI001, EPI 001
- 纯度:>98%
- 应用:Androgen Receptor antagonist
- 作用机制:Antagonist