- 名称:GNF-7
- 简介:GNF-7 is a potent type-II kinase Bcr-Abl inhibitor with IC50 of <5 nM, 61 nM, 122 nM, 136 nM, and 133 nM for M351T, T315I, E255 V, G250E, and c-Abl, respectively.
- CASNO:839706-07-9
- 分子式:C28H24F3N7O2
- 分子量:547.53
- SMILES:O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC=C(C)N=C4)N=C3N(C)C2=O)=C1)C5=CC=CC(C(F)(F)F)=C5
- 保持条件:at -20°C 3 years Powder
- 同名:GNF7, GNF 7
- 纯度:>98%
- 应用:Bcr-Abl inhibitor
- 作用机制:Inhibitor