- 名称:UNC-2025
- 简介:UNC-2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.
- CASNO:1429881-91-3
- 分子式:C28H41ClN6O
- 分子量:513.12
- SMILES:CN1CCN(CC2=CC=C(C3=CN([C@@H]4CC[C@@H](O)CC4)C5=NC(NCCCC)=NC=C35)C=C2)CC1
- 保持条件:at -20°C 3 years Powder
- 同名:UNC 2025, UNC-2025
- 纯度:>98%
- 应用:Dual MER/FLT3 inhibitor
- 作用机制:Inhibitor