- 名称:LOXO-101 (ARRY-470, Larotrectinib)
- 简介:LOXO-101 is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC.
- CASNO:1223403-58-4
- 分子式:C21H22F2N6O2
- 分子量:428.44
- SMILES:O=C(N1CC[C@@H](C1)O)NC2=C3N=C(N4CCC[C@@H]4C5=CC(F)=CC=C5F)C=CN3N=C2
- 保持条件:at -20°C 3 years Powder
- 同名:LOXO 101, LOXO101, ARRY470, ARRY 470
- 纯度:>98%
- 应用:TRK inhibitor
- 作用机制:Inhibitor