- 名称:IQ 3
- 简介:IQ 3 is a selective JNK3 inhibitor (Kd values are 66, 240 and 290 nM for JNK3, JNK1 and JNK2 respectively). Inhibits NF-kB/AP1 transcriptional activity in THP1-Blue cells (IC50 = 1.4 μM). Also inhibits TNF-α and IL-6 production in vitro.
- CASNO:312538-03-7
- 分子式:C20H11N3O3
- 分子量:341.32
- SMILES:C1=CC=C2C(=C1)C3=NC4=CC=CC=C4N=C3C2=NOC(=O)C5=CC=CO5
- 保持条件:at -20°C 3 years Powder
- 同名:IQ3, IQ-3
- 纯度:>98%
- 应用:JNK3 inhibitor
- 作用机制:Inhibitor