• 名称：UNC 9994 hydrochloride
• 简介：UNC 9994 hydrochloride, unique, beta-arrestin-biased functionally selective dopamine D2 receptor (D2R) agonist (Ki value 30 nM; EC50 value 50 nM in ??-arrestin-2 recruitment assay) that exhibits antipsychotic activity in vivo. UNC9994 markedly inhibited PCP-induced hyperlocomotion in wild-type mice, which effect was completely abolished in ??-arrestin-2 knockout mice.
• CASNO：1354030-51-5
• 分子式：C21H23Cl3N2OS
• 分子量：457.84
• SMILES：C1CN(CCC1C2=C(C(=CC=C2)Cl)Cl)CCCOC3=CC4=C(C=C3)SC=N4.Cl
• 保持条件：at -20°C 3 years Powder
• 同名：UNC9994 hydrochloride
• 纯度：>98%
• 应用：dopamine D2 receptor agonist
• 作用机制：Agonist