- 名称:A-1155463
- 简介:A-1155463 is a highly potent and selective BCL-XL inhibitor, A-1155463 shows picomolar binding affinity to BCL-XL (Ki = <0.01 nM), and >1000-fold weaker binding to BCL-2 (Ki = 80 nM) and related proteins BCL-W (Ki = 19 nM) and MCL-1 (Ki > 440 nM)
- CASNO:1235034-55-5
- 分子式:C35H32FN5O4S2
- 分子量:669.79
- SMILES:O=C(C1=C(CCCOC2=CC=C(C#CCN(C)C)C=C2F)SC(N3CC4=C(C=CC=C4C(NC5=NC6=CC=CC=C6S5)=O)CC3)=N1)O
- 保持条件:at -20°C 3 years Powder
- 同名:A 1155463, A1155463
- 纯度:>98%
- 应用:BCL-XL inhibitor
- 作用机制:Inhibitor