- 名称:Dolutegravir Sodium
- 简介:Dolutegravir sodium is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
- CASNO:1051375-19-9
- 分子式:C20H18F2N3NaO5
- 分子量:441.36
- SMILES:CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+]
- 保持条件:at -20°C 3 years Powder
- 同名:DTG, GSK1349572
- 纯度:>98%
- 应用:HIV integrase inhibitor
- 作用机制:Inhibitor