- 名称:HIF-2a Translation Inhibitor
- 简介:HIF-2a translation inhibitor (IC50 value 5 uM); Decreases HIF-2a protein and HIF-2a target gene expression in normoxia and hypoxia independent of HIF-2a mRNA expression or HIF-2a protein stability, and independent of mTOR activity. Moreover, the translation inhibitor 76 enhances binding of IRP1 to the HIF-2a IRE (Iron-Responsive Element).
- CASNO:882268-69-1
- 分子式:C9H9N3O4S2
- 分子量:287.31
- SMILES:COC(=O)C1=C(C=CS1)NN=C(C#N)S(=O)(=O)C
- 保持条件:at -20°C 3 years Powder
- 同名:N/A
- 纯度:>98%
- 应用:HIF-2a translation inhibitor
- 作用机制:Inhibitor