• 名称：NS-018 maleate
• 简介：NS-018 maleate is an ATP-competitive small-molecule inhibitor of JAK2 with IC50 of 470nM in Ba/F3-JAK2V617F cells . have30-50-fold greater selectivity for JAK2 over other JAK-family kinases, such as JAK1, JAK3 and tyrosine kinase 2.
• CASNO：1354799-87-3
• 分子式：C25H24FN7O4
• 分子量：505.5
• SMILES：CC(C1=CC=C(C=C1)F)NC2=CC(=CC(=N2)NC3=NC=CN=C3)C4=CN(N=C4)C.C(=CC(=O)O)C(=O)O
• 保持条件：at -20°C 3 years Powder
• 同名：NS018 maleate, NS 018 maleate
• 纯度：>98%
• 应用：JAK2 inhibitor
• 作用机制：Inhibitor