- 名称:(+)-Apogossypol
- 简介:(+)-Apogossypol is a potent inhibitor of Bcl-2 family proteins; competing with the BH3 peptide-binding sites on Bcl-2, Bcl-XL, Mcl-1, Bcl-W, and Bcl-B, but not Bfl-1, with IC50s of 0.5 to 2 μM.
- CASNO:66389-74-0
- 分子式:C28H30O6
- 分子量:462.53
- SMILES:CC(C=C1C(C(C)C)=C(O)C(O)=CC1=C2O)=[C@]2[C@@]3=C(C)C=C4C(C=C(O)C(O)=C4C(C)C)=C3O
- 保持条件:at -20°C 3 years Powder
- 同名:Apogossypol, NSC736630
- 纯度:>98%
- 应用:Bcl-2 family inhibitor
- 作用机制:Inhibitor